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The purpose of this study is to compare pembrolizumab (MK-3475) in combination with sacituzumab govitecan with pembrolizumab alone with respect to progression-free survival (PFS) and overall survival (OS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by blinded independent central review (BICR) among adults with metastatic non-small cell lung cancer (NSCLC) with programmed cell death ligand 1 (PD-L1) tumor proportion score (TPS) ≥50%).
NATIONAL TRIAL REFERENCE NUMBER | NCT05609968 | |
Conditions | Carcinoma, Non-Small-Cell Lung | |
Age Range | 18+ | |
Sex | All | |
Current trial phase | 1 | |
Trial start and end dates | [02-06-2023] [08-23-2028] |
Only a qualified healthcare professional can determine if you are eligible to take part in a clinical trial. However, this information may be useful in starting a conversation with your doctor.
Conditions
Carcinoma, Non-Small-Cell Lung
The drug you get will depend on which group you are placed in. This trial has 2 groups.
Group 1 will get pembrolizumab with sacituzumab govitecan (SG)
Group 2 will get pembrolizumab alone
In Phase 3 trials, researchers try to find out if a treatment works in a large number of people, usually about 1,000 to 5,000 participants who have the health condition the treatment is intended to treat. In vaccine trials, the participants may be healthy or have diseases or conditions. Phase 3 trials may happen in a doctor’s office, a clinic, or a hospital.
Locations shown may have changed in some cases. Please call the number listed in the location results to confirm the nearest trial site. Talk with a trial site member for more information.