Active, Not Recruiting

Trial purpose

This is a randomized, active-controlled, double-blind clinical study designed to evaluate the antiretroviral activity, safety and tolerability of doravirine/islatravir (DOR/ISL [MK-8591A]) in treatment-naïve participants with human immunodeficiency virus type 1 (HIV-1) infection. It is hypothesised that DOR/ISL is non-inferior to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as assessed by the percentage of participants with HIV-1 ribonucleic acid (RNA) <50 copies/ml at Week 48.

View full trial information on Clinicaltrials.gov
NATIONAL TRIAL REFERENCE NUMBER NCT05705349
Conditions HIV-1 Infection
Age Range 18+
Sex All
Current trial phase 1
Trial start and end dates [03-08-2023] [08-05-2029]

About the trial

Eligibility

Only a qualified healthcare professional can determine if you are eligible to take part in a clinical trial. However, this information may be useful in starting a conversation with your doctor.

Conditions

HIV-1 Infection

View full trial eligibility

Trial Phase 3

In Phase 3 trials, researchers try to find out if a treatment works in a large number of people, usually about 1,000 to 5,000 participants who have the health condition the treatment is intended to treat. In vaccine trials, the participants may be healthy or have diseases or conditions. Phase 3 trials may happen in a doctor’s office, a clinic, or a hospital.

Trial locations (0)

Locations shown may have changed in some cases. Please call the number listed in the location results to confirm the nearest trial site. Talk with a trial site member for more information.

What can you do next?

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NATIONAL TRIAL REFERENCE NUMBER

NCT05705349

When you talk with your doctor or clinical trial team member, please have the national trial reference number available.

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