Study Overview

Researchers are looking for new ways to treat people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL and SLL are types of blood cancer. Researchers want to know if people who take nemtabrutinib compared to those who take the standard treatments in this study will live longer without their cancer growing, spreading or returning (progression free survival).

View full trial information on Clinicaltrials.gov

NATIONAL TRIAL REFERENCE NUMBER

NCT05624554

When you talk with your doctor or clinical team member, please have the national trial reference number available.

Resources

Patient Participation

Only a qualified healthcare professional can determine if you are eligible to take part in a clinical trial. However, this information may be useful in starting a conversation with your doctor.

Conditions

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Age Range

18+

Sex

All

Study Details

All patients who enroll in the trial will receive medication while on the study.

50% of patients will receive nemtabrutinib

50% of patients will receive either fludarabine plus cyclophosphamide plus rituximab (FCR) or bendamustine plus rituximab (BR)

Trial Phase

Trial Phase 3

In Phase 3 trials, researchers try to find out if a treatment works in a large number of people, usually about 1,000 to 5,000 participants who have the health condition the treatment is intended to treat. In vaccine trials, the participants may be healthy or have diseases or conditions. Phase 3 trials may happen in a doctor’s office, a clinic, or a hospital.

Start Date

End Date

  • Actual study start date 03-16-2023
  • Estimated primary completion date 05-19-2027
  • Estimated study completion date 03-17-2031

Trial Locations

Sorry, there are no locations found.

What can you do next?

If you think this clinical trial might be a good fit and you are interested in taking part, take the next step to see if you are eligible.

Taking part in a clinical trial is an important decision

If you are considering joining a clinical trial, first learn as much as you can about:

  • The investigational treatment that is being studied
  • What the risks and possible benefits are for participants

Talk to your doctor about the clinical trial before you decide to join

 

Read out “What to Consider” page for more questions to ask and think about

NATIONAL TRIAL REFERENCE NUMBER

NCT05624554

When you talk with your doctor or clinical team member, please have the national trial reference number available.

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