Study of Belzutifan Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer

Trial Information
Eligibility
Locations
Next steps

Active, Not Recruiting

Trial Purpose

The purpose of this study is to assess the efficacy and safety of belzutifan (MK-6482) plus fulvestrant compared to everolimus plus endocrine therapy (ET) (investigator’s choice of fulvestrant or exemestane) in adults with estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) unresectable metastatic breast cancer. There is no formal hypothesis testing in this study.

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	National Trial Reference Number	NCT06428396
	MSD Protocol ID	MK-6482-029
	Conditions	Metastatic Breast Cancer
	Age Range	18+
	Sex	ALL
	Trial Phase	2
	Start Date End Date	2024-11-27 2028-12-25

Study Details

Patient Participation

Only a qualified healthcare professional can determine if you are eligible to take part in a clinical trial.

Conditions

Metastatic Breast Cancer

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Trial Phase 2

In Phase 2 trials, researchers try to find out if a treatment works in about 100 to 500 participants – usually people who have the health condition the treatment is intended to treat. In vaccine trials, the participants are usually healthy. Phase 2 trials may happen in a doctor’s office, a clinic, or a hospital.

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Trial Locations

Locations shown may have changed in some cases. Please call the number listed in the location results to confirm the nearest trial site. Talk with a trial site member for more information.

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What can you do next?

If you think this clinical trial might be a good fir and you are interested in taking part, take the next step to see if you are eligible.

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The investigational treatment that is being studied
What the risks and possible benefits are for participants

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Clinicaltrials.gov Identifier

NCT06428396

When you talk with your doctor or clinical trial team member, please have the trial identifier number or the EudraCT number available.